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How does albinism work?

How does albinism work?
Posted 2024-10-31 10:19:04
Hi everyone, so either some wolves are bugged or I don't understand something so here I am.

The way I understand it, and how it's stated, a wolf needs two copies of albinism to have the mutation. So Alb/Alb

And let's say a normal wolf is N/N

If I breed an albino wolf with a normal wolf, we get one random gene from one parent, one random gene from another parent. In this case, the puppies can only be Alb/N, so carriers, no albino, no non carrier. Right ?

Then why is this wolf not a carrier? You'll see in the family tree that her mom is albino.

I also saw this on others wolves. What am I not getting?

Thx in advance

Cloud
#136761

Posted 2024-10-31 10:31:27
There's a small chance of getting an alb carrier, this goes for all carriers as well.

If you breed an a full Albino (alb/alb) to a normal wolf, there's a chance of getting no carriers (n/n) or alb carrier (alb/n) who won't show up as Albino.
The only way to get a full Albino is to breed 2 carriers for Albino, so in the instance above, you wouldn't be able to breed a full Albino

Carriers are wolves that have the gene but do not fully show the mutation (looks like a normal wolf). Theres a small chance to get carriers, so there's not a 100% chance you will get a carrier in a litter.

🍇 Winter Uva Wine 🍇
#100703

Posted 2024-10-31 10:35:58
So it's just decided to not make sense gene wise ? Because in real life
Alb/Alb + N/N ONLY gives Alb/N

Cloud
#136761

Posted 2024-10-31 11:12:25
Technically, it is how it works in real life
They're recessive genes and it's not a guarantee that the gene will pass. You might be thinking about the box method, but it's not as easy as that. It's better to think of it in pass rates of percentage rather than that way
Im not exactly sure what the percentage of passing is but think of it like every pup in the litter only has a 10% chance of getting the gene, and to breed the full albino will have a lower chance probably

🍇 Winter Uva Wine 🍇
#100703

Posted 2024-10-31 11:52:19 (edited)
Alright so I looked it up and it is like that in real life but it's because there's multiple genes (19 in humans) involved so if you're affected on one gene and your partner is affected on another gene the kid isn't albino. But it is still a carrier of that one gene you're affected.

I just think the FAQ could be clearer because they portray it as "only one gene is involved: the albino gene". Or if there's only one gene involved, and you're affected on both alleles, then you pass it down. The fact that it's recessive doesn't mean it doesn't pass to the kid, only that the kid needs two to show the mutation. And if one parent is Alb/Alb, it can only pass down Alb since it doesn't have any unaffected gene, so the kid can only be a carrier.

I think I'm thinking of the box method? But I'd need an exemple of where it doesn't work like that in real life because it's how we decide which dog to breed to which dogs to avoid diseases that are genetically identified, in dog breeding. And if you breed an affected dog of a single gene disease to a clear dog, you get carriers. Same with colors percentages in the litter.

But I understand that's we're on a game and it was decided another way. Thanks for your answer !

Edit: they explain it here link

Cloud
#136761

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